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Coronary artery disease

coronary artery disease means the arteries supplying the heart have narrowed, it is common, and it is one of the most treatable conditions in medicine. The next question is whether the narrowing is stable or whether symptoms suggest an acute change.

What narrowing means

Coronary arteries carry blood to the heart muscle. In coronary artery disease, plaque builds up in the artery wall and can narrow the channel where blood flows.

Narrowing can be silent, especially when the heart is resting. Symptoms are more likely when the heart asks for more oxygen and blood flow, such as during walking, stairs, emotional stress or cold weather.

Artery narrowing visualiser

Move through the stages to see how plaque can change the channel for blood flow. The picture explains the idea only; it does not measure your arteries or diagnose your symptoms.

Normal artery selected. The channel is open; symptoms from artery narrowing are not expected from this picture alone.

Normal artery A simplified heart artery with an open channel for blood flow. Normal artery Open channel; symptoms are not expected from narrowing in this picture. Mild plaque Often silent; it may matter more as a risk marker than as a symptom cause. Moderate narrowing Flow may be enough at rest but less comfortable when demand rises. Severe narrowing Can cause predictable exertional symptoms; sudden change can be urgent.

Stable angina and acute events

Stable angina is a pattern: chest discomfort or breathlessness appears with exertion or emotional stress, then settles when the heart's demand falls. That is the classic pattern because a narrowed artery may supply enough blood at rest but not enough when the heart is working harder.

An acute event is different. A plaque can suddenly change and a clot can reduce blood flow quickly, so symptoms may be new, severe, occur at rest, or feel unlike the person's usual pattern.

When symptoms should not wait

Chest discomfort at rest, a new or rapidly worsening pattern, fainting, severe breathlessness, or feeling acutely unwell should be assessed urgently.

Use your GP or NHS 111 for urgent same-day advice today if symptoms are not in the 999 group above; call 999 if there is chest discomfort at rest, fainting, breathlessness that stops normal speech, feeling acutely unwell, or a sense of immediate danger. severe; call 999 if they are severe or you feel in immediate danger.

What treatment discussions usually cover

Doctors usually think in categories. One category lowers future risk by addressing cholesterol, blood pressure, diabetes, smoking and clotting risk where relevant. Another category treats angina symptoms by reducing how hard the heart has to work or by improving blood flow.

Procedures are another category. Coronary angioplasty with a stent and coronary bypass surgery are ways to improve blood flow in selected artery patterns. The choice depends on symptoms, scan results, overall health, medicine risks and what matters to the person being treated.

What to bring to an appointment

Bring the report that mentioned coronary artery disease, any ECGs or scan letters, a current medicine list, and a simple symptom timeline. Useful details are what brings symptoms on, what settles them, whether the pattern is changing, and what you can normally do before symptoms appear.

This page cannot tell you whether a narrowing needs tablets, a stent, bypass surgery or no change. It can help you understand the words and ask clearer questions.

Evidence behind this page

Major guidelines describe coronary artery disease as plaque accumulation in the coronary arteries, separate chronic coronary syndromes from acute coronary syndromes, and stress that symptom pattern and clinical context guide assessment.

Sources: Vrints C, Andreotti F, Koskinas KC, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes. European Heart Journal. doi:10.1093/eurheartj/ehae177. Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. European Heart Journal. doi:10.1093/eurheartj/ehad191. Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC guideline for the evaluation and diagnosis of chest pain. Journal of the American College of Cardiology. doi:10.1016/j.jacc.2021.07.053.

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